Testolone (RAD140)

Published on April 3, 2019

What is Testolone?

Testolone, also referred to as RAD140, is an investigational drug with muscle building and cancer benefits. It is mostly used by athletes and bodybuilders to increase their muscle mass, although it is yet to be approved for use by human.

Testolone is categorized as a SARM – Selective Androgen Receptor Modulator. SARM binds the receptors known as androgen receptors found in different parts of the body. These androgens are a group of steroid hormones that interact normally with the receptors.

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Testolone VS Testosterone

Some androgens such as dihydrotestosterone, testosterone, and androstenedione, are produced by the body naturally. The effects of SARMs and testosterone are similar because, they concentrate on a particular receptor. These effects may include: influence on the muscles, bones, and liver.

People prefer SARM because they concentrate on specific areas of the body, particularly the muscle and bone tissues, but have little to no effect on other areas.

For this reason, SARMs are able to treat disorders specifically related to muscle wasting and hormones with minimal side effects, and they are preferred to steroids or testosterone for bodybuilding.

Steroids and Testosterone are very powerful and active in increasing muscle growth, but they have several side effects on the reproductive and prostate organs.

Who Would Use it?

RAD140 is good for men suffering from low testosterone, but cannot adopt the Testosterone Replacement Therapy (TRT), although they still want to maintain their normal body activities such as physical and sexual performance.

Testolone is still undergoing research to ascertain its beneficial effect in fighting breast cancer, muscle mass increase, and protecting the brain cells. Even though it has not been approved for use by human, bodybuilders use it to increase endurance and strength.

Although it is legal to use this drug, but it’s banned in professional sports. All SARMs including RAD-140, are prohibited by the World Anti-Doping Agency.

How RAD140 Works

RAD140 is an active SARM which causes the hormonal receptors in the muscle tissue to behave in the same way as having a raise in the testosterone level. This mechanism activates similar benefits of using steroids, but without the side effects.

This drug works by blasting the cells of the muscle with a small increase in the testosterone level, to create anabolic effects on the body which may include: elimination of fats and increase in the muscle mass of the body.

A similar scenario is experienced when testosterone is impacted on the body in larger doses but with no side effect such as risk of heart failure, enlarged muscles of the heart, and hypertension.

Benefits of RAD140

1. Helps in Breast Cancer

Androgen and estrogen receptor positive (AR/ER+), is a form of breast cancer with a high sensitivity to hormones. SARMs such as RAD-140 are the medications that has the potentials to fight this common cancerous growth by affecting the receptors.

Study shows that, testolone inhibits the growth of cancerous cells by blocking the estrogen effects. RAD140 suppresses the gene responsible for producing estrogen receptors known as estrogen receptor 1 gene. When the receptors are insufficient, the estrogen will be rendered inactive and powerless.

2. Loss of Weight

The use of SARMs reduces body fat but increases the muscle mass. A research conducted on monkeys to know the effects of RAD-140 on fat and muscles showed an increase in lean muscles, while its effects on body fats were unknown.

testolone rad140 results before and after

The study also proved that, cholesterol levels could be improved with testolone. Also, the use of energy may be increased by a larger muscle mass which further promotes loss of fats.

3. Increase in Muscle Mass

Testolone is well-known to bodybuilders due to its muscle building abilities. Like other SARMs, RAD140 concentrates only on specific areas of the body without causing the unwanted effects experienced when using conventional steroids. Clinical approval for the use of RAD-140 is very limited despite its popularity, and human study of testolone is yet to be conducted.

In a research done on some monkeys to examine the effects of testolone on muscle growth, it was realised that, after about 28 days of usage, there was an increase in the lean muscle mass.

testolone rad140 cycle dosage

4. Helps Brain Cells

Androgen plays a good role to protect the brain by promoting the growth of brain cells, improving memory, and decreasing the accumulation of amyloid beta proteins, which are the main causes of the disease known as the Alzheimer disease. When a study was conducted on mice, the nerves in the brain were protected by RAD140 against injury from amyloid beta.

Testosterone and testolone were also effective in fighting neurotoxins. Users of RAD140 confirmed that, it gives a better sleep and promotes sexual performance, although there is no clinical proof to this yet. The ability of this compound to increase sexual performance may be due to its testosterone-mimicking capability.

Buy Testolone (RAD140)

How To Use It


RAD-140 has no specified dosage since it is yet to be clinically tested on human, but resources for bodybuilders and athletes, recommends a daily dose of 10 to 30mg for men, and 5 to 10mg for women.

Users usually adopt the 8 to 12 weeks cycle of RAD140, although the off-cycle may vary. There are users who prefer a short cycle of 6 to 8 weeks.

When a research of this drug was conducted on monkeys, the body absorbed about 70% of it when ingested. This proves that, testolone has a good bioavailability.


Some users combine testolone with steroids or other SARMs to get more benefits. This drug may be stacked with Ibutamoren, Ostarine, or with steroids such as Primobolan. The combination of testolone with Ostarine improves recovery, and it can also be used with Cardarine for endurance gains or cutting.


It is an established fact that, RAD140 helps in building muscle tissues. So, it is important to eat diets that are high in protein, coupled with good training, while supplementing with testolone.

When bulking, you must ensure that the muscles are stimulated constantly, to give effective results, otherwise you may be disappointed.

Post Cycle Therapy

The inability of the body to produce testosterone may be caused by the use of steroids and SARMs which might depend on dosage, duration of usage, and the user.

Post Cycle Therapy (PCT) is recommended by experienced users after a cycle of testolone. This therapy involves restoring the hormone levels by taking Clomid or Nolvadex, and its duration may vary depending on how long the SARM was used. Taking PCT for 3 to 4 weeks is usually ideal.

Side Effects

Testolone has no side effect due to its estrogenic nature, and clinical studies on rats and monkeys showed no side effect with its usage.

Some users of this drug might experience hair loss, headache, or nausea, but no proof has confirmed its link with them.

The only side effect a user might experience if RAD-140 is taken in large quantities for a long time is hormone suppression. When your natural hormone production is suppressed, you’ll need a Post Cycle Therapy (PCT) to help recover your hormones.

Where To Buy RAD140 (Testolone)

RAD-140 is available for purchase from online stores, but to be sure of buying a genuine product, esarms is highly recommended.

eSARMS is currently the best SARM supplier and one of the few SARM stores that ships internationally. They have a high-purity testolone which gives better results than others. Having used them severally, I have no reservations to recommend them.


Testolone (RAD140) is a popular SARM due to its muscle-building effects. There are no known side effects for its usage apart from the suppression of hormones production due to its prolonged use in large quantities.

Few users may report some side effects such as decreased sex drive, hair loss, and mood swing, but there is no evidence linking it to these effects.

Testolone is banned in professional sports. Users should purchase SARMs only from reliable online stores, because there are many online stores that sells these products but they do not contain the ingredients advertised.

Overall, studies and anecdotal proofs suggest that, testolone has good potentials, but its long-term and safety risks on human is yet to be known.

Testolone Review
  • Increas Lean Muscle
  • Promote Fat Loss
  • Boost Libido
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