Cardarine (GW-501516)05:25

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Published on March 16, 2019

Before 1992, no one had heard the name “Cardarine” It came about from the collaboration between Lingard pharmaceuticals and GSK. The original intent for creating the drug was to provide leverage in the fight against cardiovascular disease and metabolic diseases. Unfortunately, in 2007, the seeming breakthrough was abandoned. This was before they discovered that Cardarine could serve another purpose- enhance performance.

What is Cardarine?

Cardarine (GW-501516) is a performance-enhancing drug that makes it possible for the body to expend energy even at a state of rest. It burns body fat and recovers the sensitivity of the insulin. As a result, it improves protein fusion. Put in a simpler and less complicated way, Cardarine gives you bigger muscles, reduces your fat, increases your recovery period, and all-around endurance.

These endearing qualities of Cardarine unsurprisingly, made it a hot catch among athletes. Contrary to many beliefs, cardarine is not a steroid, and it is not a supplement. It is just a drug that can amplify your physical performance beyond what you can imagine.

Is Cardarine legal?

Before we proceed, it is important that we discuss the legality of the drug.  The circumstance of use is the yardstick for measuring the legality of the drug. In 2009, the World Anti-Doping Agency added the drug to its list of prohibited drugs on the ground of health risk. A breach of this prohibition would attract the maximum penalty by the association.

It is also illegal to sell cardarine as a dietary supplement or as food consumption. It is, however, consider legal to sell cardarine as a research chemical formula or as medicine directed at treating cholesterol, obesity and so on. But for athletes, its performance-enhancing capacity makes it illegal.

How does it work?

cardarine results before and after

Cardarine works well for endurance and fat loss. The drug allows GW-501516 function is aimed at the androgen receptors that prompts glucose to the muscle tissue. Increased glucose means increased energy and a significant reduction in fat storage. So it allows you to push yourself to the extreme without getting short of breath or easily worn out.

This study demonstrated that 3-week treatment with GW501516 increased running performance of both trained and untrained mice. Like training, GW501516 promoted mitochondrial fatty acid oxidation and increased fat metabolism in muscle tissue.

Sci Rep. 2015; 5: 9884.

How to use it

At this point, we feel it is safe to point out the fact that there has not been extensively clinical study for human effect. Most of the documented studies have been carried out on mice. It is suggested that the dosage is kept between 10mg/ml. You should use GW once daily as its effect can last for 24 hours or you can divide the dose into two – morning and evening. Either way, you can use it before the workout or as a split dosage.

As an extreme, some recommend a dose of 20mg once daily. But that is the limit you can have. Cardarine is available in its liquid form. You can administer GW-501516 via a drop applicator or by mixing it with water.

Benefit and result of using Cardarine

 Fat utilization:

Cardarine increase the amount of glucose in the body. By doing so, it strips the body of fat and makes you look ripped and leaner. It also decreases triglycerides, VLDL proteins, and fatty acid.

Builds stamina and energy:

This is why WADA banned it. Cardarine increases the performance of the user with multiple folds. It gives you better stamina energy and performance capacity. GW-501516 ensures that there is a constant flow of energy in the body.

Bigger muscles:

When you have enough glucose, stamina, and energy to run rounds at your gym, without any doubt, you would develop bigger and stronger muscles.

Obesity:

GW-501516 reduces obesity caused by insulin resistance and reduce chronic inflammation. As it makes use of fat rapidly, it reduces the risk of gaining weight from a diet.

Fast and sharp:

Cardarine produces the desired results minutes after taking. You can use GW501516 alone or combine it with other compounds.

Enhanced endurance:

GW-501516 enhances oxygen utilization by the body. It allows you to breathe more, recover fast, and lessen muscle soreness.

What are the side effects?

From the clinical research conducted on mice, it shows that it is not safe to use during pregnancy, and it causes cancer. This was why the drug was abandoned initially. However, humans have shown no significant side effects.

In 2008, The American Association of Cancer Research showed that Cardarine can potentially reduce the development of cancer in humans. Another study in Australia considered men who used the drugs for about 6 months and recorded no side effects.

This study provides further evidence that GW501516-activated PPARβ/δ reduces TNFα-induced Nfkb1 activity and inflammatory signaling via direct induction of anti-inflammatory genes, as well as indirect inhibition of pro-inflammatory genes by BCL6 dissociation in human pancreatic cancer cells.

Biochem Biophys Rep. 2016 Dec; 8: 395–402.

Conclusion

Cardarine is a highly sought after drug by athletes and bodybuilders all around the World. Better muscle, better result, improved endurance, and longer stamina. So much use that its effect cannot be disputed. Although no side effect has come to light, it is recommended that you give a space of 3 months between use to ensure rest for the body.

Cardarine Review
  • Reduce Fat
  • Boost Endurance
  • Lean Muscle Mass Gains
  • Speed Up Recovery
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